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Article

[Prognostic significance of IKZF1 alterations in acute B-lymphoblastic leukemia and the choice of transplantation strategy].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 14 May 2026

Ma X X, Jiang E L

Abstract excerpt

Gene alterations in Ikaros family zinc finger protein 1 (IKZF1) are common genetic abnormalities in B-cell acute lymphoblastic leukemia (B-ALL) and are closely associated with an increased risk of relapse and poor prognosis. In this study, the biological functions of the IKZF1 gene and the clinical significance of its various mutation types were systematically elaborated. Accordingly, a comprehensive clinical...

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Identifiers

PMID: 42409742
DOI: 10.3760/cma.j.cn121090-20250826-00400
PMCID: PMC13416543

Genes

IKZF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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