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Clinical Relevance and Applicability of the 2022 World Health Organization Classification of Childhood B Lymphoblastic Leukemia in the Context of MRD-Directed Therapy

2024-10-28

Abstract excerpt

<title>Abstract</title> <p>WHO5-2022 classification of B-lymphoblastic leukemia (B-ALL) incorporates several novel entities requiring high-throughput sequencing for their accurate characterization. The clinical relevance of this classification in the context of contemporary MRD-directed therapy is unclear. We analyzed 533 pediatric B-ALL uniformly treated with ICiCLe-ALL-14 protocol as defined by WHO2016 and recl...

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Literature Corpus work: 329d407b-11d0-5641-b185-17e8cda9ce9f
DOI: 10.21203/rs.3.rs-5303520/v1

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