Article
Triparental synthetic yeast hybrids as a platform for higher 2-phenylethanol yields and stress resistance.
World journal of microbiology & biotechnology - 6 Jul 2026
Drężek Karolina, Antunovics Zsuzsa, Sobczyk Maria Krystyna, Grabiec Agnieszka Karolina, Mierzejewska Jolanta
Abstract excerpt
2‑Phenylethanol (2‑PE) is a valuable aromatic alcohol widely used in the cosmetic, food, and pharmaceutical industries, yet its cytotoxicity remains a major bottleneck for microbial production. In this study, we evaluated a set of previously constructed triple hybrid yeast strains (H1-H5), derived from S. cerevisiae 10‑170 and the double hybrid II/6, to assess their potential for enhanced 2‑PE biosynthesis and...
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