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Article

Investigation of the Relationship Between Antibody-Mediated Rejection and Serum Interleukin 40 Levels in Heart Transplant Patients.

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation - 1 May 2026

Yavaşcaoğlu Üney Begüm, Ozdemir Handan, Sezgin Atila, Kavuzlu Miray, Başturk Bilkay, Verdi Hasibe

Abstract excerpt

OBJECTIVES: Heart transplant remains the definitive treatment for end -stage heart failure; however, long -term graft survival is often compromised by immune -mediated injury. Antibody -mediated rejection is primarily driven by donor -specific antibodies synthesized by Blymphocytes. Interleukin 40 has been associated with B -cell -mediated autoimmune pathologies, suggesting a role in donor -specific antibody...

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Identifiers

PMID: 42388167
DOI: 10.6002/ect.2026.0114

Genes

CD19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 15 Oct 2026.

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