Article
Humoral immunity in phenotypes of chronic lung allograft dysfunction: A broncho-alveolar lavage fluid analysis.
Transplant immunology - 1 Sept 2016
Vandermeulen Elly, Verleden Stijn E, Bellon Hannelore, Ruttens David, Lammertyn Elise, Claes Sandra, Vandooren Jennifer, Ugarte-Berzal Estafania, Schols Dominique, Emonds Marie-Paule, Van Raemdonck Dirk E, Opdenakker Ghislain, Verleden Geert M, Vos Robin, Vanaudenaerde Bart M
Abstract excerpt
BACKGROUND: Recently, antibody mediated rejection (AMR) has been associated with a higher incidence of chronic lung allograft dysfunction (CLAD) and mortality after lung transplantation (LTx). We investigated markers related to AMR and matrix remodeling in CLAD, with special attention for its two phenotypes being bronchiolitis obliterans syndrome (BOS) and restrictive CLAD (rCLAD). METHODS: Immunoglobulins (IgA,...
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