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Article

Anti-idiotypic antibodies specific for HLA in heart and kidney allograft recipients.

Immunologic research - 1 Jan 1993

Reed E, Ho E, Cohen D J, Ramey W, Marboe C, D'Agati V, Rose E A, Hardy M, Suciu-Foca N

Abstract excerpt

Chronic rejection is the major threat to both heart and renal allograft survival. We have explored the possibility that some patients with anti-donor HLA antibodies (Ab1) develop specific anti-idiotypic antibodies (Ab2) which suppress the production of Ab1, and subsequently, the progression of ch...

Topics

Alleles
Antibodies, Anti-Idiotypic
Genotype
Graft Survival
HLA Antigens
HLA-DR Antigens
HLA-DRB1 Chains
Heart Transplantation
Histocompatibility Antigens Class II
Humans
Isoantibodies
Kidney Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8515181
DOI: 10.1007/BF02918364

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8515181-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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