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Article

Generation of Antigen Microarrays to Screen for Autoantibodies in Heart Failure and Heart Transplantation.

PloS one - 1 Jan 2016

Chruscinski Andrzej, Huang Flora Y Y, Nguyen Albert, Lioe Jocelyn, Tumiati Laura C, Kozuszko Stella, Tinckam Kathryn J, Rao Vivek, Dunn Shannon E, Persinger Michael A, Levy Gary A, Ross Heather J

Abstract excerpt

Autoantibodies directed against endogenous proteins including contractile proteins and endothelial antigens are frequently detected in patients with heart failure and after heart transplantation. There is evidence that these autoantibodies contribute to cardiac dysfunction and correlate with clinical outcomes. Currently, autoantibodies are detected in patient sera using individual ELISA assays (one for each...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26967734
DOI: 10.1371/journal.pone.0151224
PMCID: PMC4788148

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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