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Article

Tectochrysin suppresses the profibrotic phenotype of human keloid fibroblasts and is associated with reduced nuclear p65 accumulation.

Folia histochemica et cytobiologica - 1 Jan 2026

Ma Lin, Zheng Wei, Song Weibo, Ma Aijing, Zhang Qianqian, Gao Lei, Wang Hongyu

Abstract excerpt

INTRODUCTION: Keloids are fibroproliferative scars characterized by persistent fibroblast activation and excessive extracellular matrix deposition. Tectochrysin is a natural flavone with anti-inflammatory and anti-oxidative activities, but its effects on keloid fibroblasts remain unclear. MATERIAL AND METHODS: Human keloid fibroblasts (HKFs) and human skin fibroblasts (HSFs) were exposed to tectochrysin. Cell...

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PMID: 42383722
DOI: 10.5603/fhc.111687

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CCK

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