Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Keratin-Mediated Selective Inhibition in Proliferation and Selective Apoptosis of Keloid Fibroblasts

1 Jan 2025

Abstract excerpt

Keloids are pathological scars characterized by excessive proliferation of fibroblasts and abnormal extracellular matrix (ECM) accumulation, largely mediated by transforming growth factor-β1 (TGF-β1). Current therapeutic approaches often fail due to high recurrence and limited selectivity. Here, we investigate the potential of human hair-derived keratin (HK) as a biomaterial with selective anti-fibrotic activity....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatologic Treatments and Research
Share to Skin and Cellular Biology Research

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40697649
DOI: 10.34133/bmr.0231

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Keratin-Mediated Selective Inhibition in Proliferation and Selective Apoptosis of Keloid FibroblastsPMID 40697649Read ↗

Keloids – clinical diagnosis, pathogenesis, and treatment optionsSemantic proximity Read ↗

New Anti‐Fibrotic Strategies for Keloids: Insights From Single‐Cell Multi‐OmicsSemantic proximity Read ↗

Keloid disorder: Fibroblast differentiation and gene expression profile in fibrotic skin diseasesSemantic proximity Read ↗

Effect of Hypertrophic Scar Fibroblast-Derived Exosomes on Keratinocytes of Normal Human SkinSemantic proximity Read ↗

Molecular dissection of abnormal wound healing processes resulting in keloid diseaseSemantic proximity Read ↗

BMP1 Promotes Keloid by Inducing Fibroblast Inflammation and FibrogenesisSemantic proximity Read ↗

Understanding Keloid Pathobiology From a Quasi-Neoplastic Perspective: Less of a Scar and More of a Chronic Inflammatory Disease With Cancer-Like TendenciesSemantic proximity Read ↗

3D modeling of keloid scars in vitro by cell and tissue engineering.Semantic proximity Read ↗

Keloid scarring: bench and bedside.Semantic proximity Read ↗

Cartilage-like composition of keloid scar extracellular matrix suggests fibroblast mis-differentiation in diseaseSemantic proximity Read ↗

Heterogeneous response to TGF-β1/3 isoforms in fibroblasts of different origins: implications for wound healing and tumorigenesisSemantic proximity Read ↗

Deciphering the single-cell transcriptome network in keloids with intra-lesional injection of triamcinolone acetonide combined with 5-fluorouracilSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.