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Genomic outbreak investigation of biosafety-level-3 pathogens using nanopore sequencing.

Microbial genomics - 1 Jun 2026

Thomas Christine Francesca, Brangsch Hanka, Tomaso Herbert, Melzer Falk, Wareth Gamal, Linde Jörg

Abstract excerpt

Background. Accurate outbreak analysis is essential for effective infectious disease control. While short-read Illumina sequencing is the current gold standard for genotyping pathogens, Oxford Nanopore Technologies (ONT) offers advantages such as portability and real-time sequencing. However, the accuracy of ONT for single nucleotide polymorphisms (SNP) detection and core genome multilocus sequence typing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42376844
DOI: 10.1099/mgen.0.001742
PMCID: PMC13317016

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