Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lactylation-Related Genes in Ulcerative Colitis: A Multiomics Mendelian Randomization Study for Therapeutic Target Discovery.

Human mutation - 1 Jan 2026

An Na, Wang Ruiyun, Jiao Huiping, Lu Zhongwen, Dou Yafei, Zheng Laikun, Ding Zhaoliang

Abstract excerpt

Background: Ulcerative colitis (UC), a chronic and nonspecific intestinal inflammatory disease, has seen a rising incidence rate worldwide year by year. Its pathogenesis remains incompletely understood. Lactylation modification is closely related to the generation of inflammation. Exploring the pathogenesis of UC from the perspective of lactylation is of great significance for the understanding and treatment of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colitis, Ulcerative
Share to Gene Expression Profiling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Multiomics

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 42369205
DOI: 10.1155/humu/7720538
PMCID: PMC13307184

Genes

STMN1
EP300
LDHC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lactylation-Related Genes in Ulcerative Colitis: A Multiomics Mendelian Randomization Study for Therapeutic Target Discovery.PMID 42369205Read ↗

Mendelian Randomization Identifies Putative Aging-Related Causal Genes With Diagnostic Potential in Ulcerative Colitis.Semantic proximity Read ↗

Integrative biomarker discovery and immune profiling for ulcerative colitis: a multi-methodological approachSemantic proximity Read ↗

Large-scale searching for causal relationships of milk consumption with multi-omics and disease susceptibility: A phenome-wide Mendelian randomization study.Semantic proximity Read ↗

Multivariable genome-wide analysis elucidates the shared genetic architecture, immunosenescence features, and gut-origin therapeutic targets of ulcerative colitis-associated multisystem inflammation.Semantic proximity Read ↗

Integrative multi-omic analyses identify candidate targets for celiac disease involving tissue-specific regulationSemantic proximity Read ↗

Large-scale transcriptomic meta-analysis identifies novel therapeutic targets for ulcerative colitisSemantic proximity Read ↗

Systematic post-translational modification profiling identifies molecular subtypes and therapeutic targets in ulcerative colitis: evidence from multi-omics integrationSemantic proximity Read ↗

Molecular Comparison of Adult and Pediatric Ulcerative Colitis Indicates Broad Similarity of Molecular Pathways in Disease TissueSemantic proximity Read ↗

Novel insight into the gene etiology of ulcerative colitis gained from transcriptome association study and single-cell sequence analysis.Semantic proximity Read ↗

Causal Mediation Role of Immune Cells in Gut Microbiota-Pneumonia Associations: A Mendelian Randomisation Study.Semantic proximity Read ↗

A multi-dimensional approach to unravel the intricacies of lactylation related signature for prognostic and therapeutic insight in colorectal cancerSemantic proximity Read ↗

Integrative computational approach identifies immune‐relevant biomarkers in ulcerative colitisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.