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Article

Mendelian Randomization Identifies Putative Aging-Related Causal Genes With Diagnostic Potential in Ulcerative Colitis.

Annals of human genetics - 1 Nov 2025

Zhao Qi, Sun Xiangfei, Jiang Ying, Liu Qi, Zhang Di

Abstract excerpt

BACKGROUND: Aging-related immunosenescence increases the risk of ulcerative colitis (UC), and investigating aging-related causal genes in UC patients may aid in deciphering the molecular pathophysiology of UC. This study aims to identify aging-related causal genes and explore their diagnostic value and underlying mechanisms in UC. METHODS AND MATERIALS: Colonic transcriptome data, aging-related genes, genome-wide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40317733
DOI: 10.1111/ahg.12600

Genes

ERBB2
ME2
CTSB
IL24

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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