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Molecular Comparison of Adult and Pediatric Ulcerative Colitis Indicates Broad Similarity of Molecular Pathways in Disease Tissue

4 Feb 2018

Abstract excerpt

BACKGROUND: Efficacy data from adult ulcerative colitis (UC) clinical trials are often extrapolated for pediatric prescribing. Consequently, it is important to understand similarities/differences in pediatric and adult UC. Pediatric UC tends to have more extensive disease at presentation, yet genetic studies have not detected pathways that distinguish the populations, and differences in mucosal gene expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29401083
DOI: 10.1097/mpg.0000000000001898

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