Article
Genetic characterization of the TAPBP and its allelic association with BF2 in the chicken major histocompatibility complex.
Immunogenetics - 27 Jun 2026
Fernando Roshani, Agulto Trisha Nicole, Cho Eunjin, Kim Jaewon, van Hateren Andy, Kim Minjun, Manjula Prabuddha, Lee Jun Heon
Abstract excerpt
TAPBP is a key chaperone of the peptide-loading complex that facilitates peptide loading onto major histocompatibility complex class I (MHC I) molecules. This study characterized TAPBP alleles in Korean Native Chickens (KNCs), identified novel variants, and evaluated allelic associations with BF2. Thirty-six samples representing six KNC lines were genotyped using LEI0258 and the MHC-B SNP panel, and individuals...
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