Article
Diversity and evolution of the highly polymorphic tandem repeat LEI0258 in the chicken MHC-B region.
Immunogenetics - 1 Jun 2013
Chazara Olympe, Chang Chi-Sheng, Bruneau Nicolas, Benabdeljelil Khalid, Fotsa Jean-Claude, Kayang Boniface B, Loukou N'Goran E, Osei-Amponsah Richard, Yapi-Gnaore Valentine, Youssao Issaka A K, Chen Chih-Feng, Pinard-van der Laan Marie-Hélène, Tixier-Boichard Michèle, Bed'hom Bertrand
Abstract excerpt
The chicken major histocompatibility complex (MHC) is located on the microchromosome 16 and is described as the most variable region in the genome. The genes of the MHC play a central role in the immune system. Particularly, genes encoding proteins involved in the antigen presentation to T cells. Therefore, describing the genetic polymorphism of this region is crucial in understanding host-pathogen interactions....
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