Genetic insights into the major histocompatibility complex class I BF2 gene of Korean native chickens in relation to the LEI0258 microsatellite marker and the 90-SNP panel.

Abstract excerpt

The chicken major histocompatibility complex (MHC) represents a "minimal essential MHC" consisting of classical class I (BF) and class II (BL) molecules that present peptides to CD8+ cytotoxic and CD4+ helper T cells, respectively. Class I molecules, primarily encoded by the BF2 gene, are central to immune responses against pathogens. Moreover, these molecules show enormous genetic diversity driven by a molecular...

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