Article
Polymorphism of sheep MHC Class IIb gene TAPASIN.
Veterinary immunology and immunopathology - 15 Sept 2010
Subramaniam N Siva, Morgan E F, Lee C Y, Wetherall J D, Groth D M
Abstract excerpt
The Major Histocompatibility Complex (MHC) is one of the most gene dense regions in the genome and studies in several species have shown significant associations between the MHC and disease. The endoplasmic reticular glycoprotein, tapasin, is involved in the MHC class I antigen presentation pathway. Sheep TAPASIN is located in the class IIb region of the MHC. Sheep TAPASIN was subcloned from BAC and cosmid...
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