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Article

Fine-Mapping of HLA Effects in Oral and Non-Oral Lichen Planus.

HLA - 1 Jul 2026

Ritari Jarmo, Reeve Mary Pat, FinnGen Maria Siponen, Vehviläinen Mari, Salo Tuula, Osoegawa Kazutoyo, Viña Marcelo Fernandez, Goudey Benjamin, Partanen Jukka, Mignot Emmanuel J M

Abstract excerpt

Lichen planus (LP) is an inflammatory disease affecting squamous epithelia, typically manifesting in a cutaneous (non-OLP) and an oral mucosa (OLP) form, the latter conferring elevated risk of oral squamous cell carcinoma. Despite the presence of CD4+ and CD8+ T-cell infiltrates in LP lesions, specific autoantibodies or target T-cell antigens have not been identified. A recent genome-wide association study (GWAS)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42362360
DOI: 10.1111/tan.70809
PMCID: PMC13349553

Genes

CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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