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Article

IL12B rs3213094 as a Predictor of Early Response to Biologic Therapy in Psoriasis: A Real-World Study in a Romanian Cohort.

Medicina (Kaunas, Lithuania) - 28 May 2026

Matei-Man Alessandra-Madalina, Gaal Ildiko-Orsolya, Catana Andreea, Vesa Stefan, Senila Simona, Candrea Elisabeta, Orasan Meda, Puskas Alexandra, Man Ana Calina, Mocan Teodora

Abstract excerpt

Background and Objectives: Psoriasis is a chronic immune-mediated inflammatory disease characterized by heterogeneous clinical presentation and variable response to biologic therapy. Genetic variation within the IL-23/Th17 inflammatory pathway may influence treatment outcomes. This study evaluated the association between IL12B rs3213094 and IL23R rs11209026 single-nucleotide polymorphisms (SNPs) and response to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Interleukin-12 Subunit p40
Share to Polymorphism, Single Nucleotide
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Source

Open in PubMed Open full text

Identifiers

PMID: 42356054
DOI: 10.3390/medicina62061041
PMCID: PMC13304450

Genes

IL12B
IL23R
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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