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Article

Therapeutic Outcomes and Clinical Features of Advanced Non-Small Cell Lung Cancer Carrying KRAS Mutations: A Multicenter Real-life Retrospective Study.

Clinical lung cancer - 1 Nov 2022

Mazzaschi Giulia, Perrone Fabiana, Minari Roberta, Verzè Michela, Azzoni Cinzia, Bottarelli Lorena, Pluchino Monica, Armillotta Maria Pia, Ubaldi Annalisa, Altimari Annalisa, Gruppioni Elisa, Sperandi Francesca, Andrini Elisa, Guaitoli Giorgia, Bettelli Stefania, Longo Lucia, Bertolini Federica, Barbieri Fausto, Pagano Maria, Bonelli Candida, Tagliavini Elena, Nicoli Davide, Ubiali Alessandro, Zangrandi Adriano, Trubini Serena, Proietto Manuela, Gnetti Letizia, Tiseo Marcello

Abstract excerpt

INTRODUCTION: Targeting Kirsten Rat Sarcoma (KRAS) has been deemed impossible for long time, but new drugs have recently demonstrated promising results. Evidence on the outcome of KRAS-mutant advanced-NSCLC treated with new standard regimens are still scarce. Thus, we aimed at assessing the incidence and clinical impact of KRAS mutations in a real-life population of advanced-NSCLC, exploring the prognostic...

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Identifiers

PMID: 36002369
DOI: 10.1016/j.cllc.2022.07.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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