Article
Genetic Association and Clinical Relevance of TNFSF13B/BAFF and PADI4 Polymorphisms in ANCA-Associated Vasculitis: A Case-Control Study with Genetic Model Analysis in Guangxi Population.
Genes - 20 Jun 2026
Lu Jiafu, Huang Simei, Wei Shuwen, Xue Chao
Abstract excerpt
Objective:TNFSF13B, which encodes B-cell-activating factor (BAFF) and peptidylarginine deiminase 4 (PADI4), plays crucial roles in the pathogenesis of ANCA-associated vasculitis (AAV). This study investigated the associations of single-nucleotide polymorphisms (SNPs) in TNFSF13B/BAFF and PADI4 genes with AAV susceptibility, clinical phenotypes, and disease activity in a Guangxi Chinese population. Methods: A...
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