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Article

Genetically predicted serum uric acid and pulmonary arterial hypertension: Mendelian randomization with an exploratory NHANES risk-burden analysis.

Science progress - 1 Jan 2026

He Huabin, Liu Zhekang, Yu Qingyun, Fu Qingan, Zhu Huangxin

Abstract excerpt

ObjectiveSerum uric acid (SUA) has been associated with cardiovascular and pulmonary vascular disease, but whether SUA has a causal role in pulmonary arterial hypertension (PAH) remains uncertain. This study aimed to evaluate the genetic association between SUA and PAH using Mendelian randomization (MR), with an exploratory population-based analysis in individuals with a higher PAH-related risk-factor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42332868
DOI: 10.1177/00368504261463441
PMCID: PMC13305290

Genes

PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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