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Article

PARK(ing) time-How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease.

FEBS letters - 1 Jul 2026

Zientara Kamila, Skoczek Kinga, Pyza Elzbieta, Damulewicz Milena

Abstract excerpt

Sleep and circadian disruptions are early symptoms of Parkinson's disease (PD), which is one of the most common neurodegenerative disorders. However, PD has an idiopathic origin, and the factors accelerating the progression of symptoms are not fully understood. One genetic factor associated with PD is a mutation in the parkin gene, which impairs mitophagy and increases oxidative stress. In this research, we used...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42299891
DOI: 10.1002/1873-3468.70389
PMCID: PMC13404150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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PARK(ing) time-How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease.PMID 42299891Read ↗

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Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin.Semantic proximity Read ↗

Parkinson's disease-associated proteins : studying their role in mitophagy with cellular and Drosophila modelsSemantic proximity Read ↗

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