Article
Association of EFEMP1 gene polymorphisms with the risk of glioma: A hospital-based case-control study in a Chinese Han population.
Journal of the neurological sciences - 15 Feb 2015
Zhang Shuo, Ye Zhao, Song Xiao, Chen Gong, Huai Cong, Wang Qihan, Song Jianping, Lu Daru, Zhao Yao, Chen Hongyan
Abstract excerpt
BACKGROUND: EGF-containing fibulin-like extracellular matrix protein1 (EFEMP1) gene was relative with the formation and development of tumors and had an anti-angiogenic function. Recently, many studies investigating the function of EFEMP1 gene, including its roles in prostate cancer and glioma, have been reported. EFEMP1 suppressed glioma growth by modulating EGFR and AKT signaling pathway or promoted growth...
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