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Article

Cross-trait mapping of shared susceptibility across inflammatory bowel disease and spondyloarthropathies.

Journal of translational medicine - 13 Jun 2026

Wang Liangchun, Li Fangyan, Wang Jianming, Wang Hui, Gong Liping, Wang Yanqing

Abstract excerpt

BACKGROUND: Inflammatory bowel diseases (IBDs) and spondyloarthropathies (SpAs) frequently co-occur, yet the subtype-specific genetic architecture and effector tissues that implement this gut-joint coupling remain poorly defined. METHODS: We integrated European-ancestry GWAS summary statistics for IBD, Crohn's disease, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis, reactive arthritis and...

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Share to Chromosome Mapping
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Inflammatory Bowel Diseases

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait, Heritable

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Share to Spondylarthropathies

Source

Open in PubMed Open full text

Identifiers

PMID: 42286689
DOI: 10.1186/s12967-026-08326-4
PMCID: PMC13355338

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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