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Article

Exploring the shared genetic architecture of migraine and autoimmune diseases.

Human immunology - 1 Jul 2026

Chen Jun, Wu Yamei, Liu Meijun, Fan Yihua, Cao Tian, Zhao Liangbin, Long Kunlan, Wang Cixiao, Wu Ling, Lv Lizeyu, Li Haijun, Chen Xingyue, Zhi Lijia, He Yuchi, Tao Tian

Abstract excerpt

BACKGROUND: Migraine (MIG) frequently co-occurs with autoimmune diseases (ADs), but the shared genetic basis underlying this comorbidity remains unclear. METHODS: Using publicly available GWAS summary statistics from European populations, we applied an integrated framework to investigate the shared genetic architecture between MIG and seven ADs (SLE, UC, CD, PSC, T1D, RA, MS). Genetic correlations and polygenic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42081878
DOI: 10.1016/j.humimm.2026.111746

Genes

CARD9
INPP5B

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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