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Article

Genetic diversity of pangolin coronaviruses reveals a key immuno-evasive substitution at spike residue 519.

Journal of virology - 21 Jul 2026

Yo Maximilian Stanley, Kaku Yu, Kosugi Yusuke, Tolentino Jarel Elgin, Kuroda Daisuke, Cao Yunlong, Sato Kei

Abstract excerpt

Malayan pangolins are unusual hosts for several SARS-CoV-2-related coronaviruses, which have previously been known to only infect Rhinolophus bats. Much debate has hence surrounded their possible role as intermediate hosts in the emergence of SARS-CoV-2, but the virological phenotypes of most pangolin coronaviruses (pCoVs) remain unclear. Here, we comprehensively analyze all pCoVs to date identified from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42267927
DOI: 10.1128/jvi.00352-26
PMCID: PMC13386858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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