Article

Genetic diversity of pangolin coronaviruses reveals a key immuno-evasive substitution at spike residue 519

2025-04-02

Abstract excerpt

Malayan pangolins are unprecedented hosts for several SARS-CoV-2-related coronaviruses, which have previously been known to only infect Rhinolophus bats. Much debate has hence surrounded their possible role as intermediate hosts in the emergence of SARS-CoV-2, but the virological phenotypes of most pangolin coronaviruses (pCoVs) remain unclear. Here, we comprehensively analyze all pCoVs to date identified from tra...

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Literature Corpus work: 71ebda3c-03b0-5681-ad3f-5bf2ba124f75
DOI: 10.1101/2025.04.01.646621

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