Article
Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2
12 Jan 2022
Abstract excerpt
SARS-CoV-2 belongs to the Sarbecovirus subgenus of betacoronaviruses and other members in this subgenus include SARS-CoV and coronaviruses mainly found in bats 1 . It is generally believed that like SARS-CoV and MERS-CoV, SARS-CoV-2 has a natural origin and was selected either in animal hosts before zoonotic transfer, or in humans following zoonotic transfer 2 . However, the molecular determinants for host...
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