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Article

Construction of a tumor mutational burden-derived LncRNA prognostic computational framework associated with therapy sensitivity in skin cutaneous melanoma.

Journal of translational medicine - 24 Oct 2024

Li Gaohua, Wu Tingting, Li Heping, Wei Chuzhong, Sun Yuanbo, Gao Pengcheng, Huang Xinlin, Liu Zining, Li Jianwei, Wang Yanan, Li Guoxin, Fan Lei

Abstract excerpt

BACKGROUND: Skin cutaneous melanoma (SKCM) poses a significant public health challenge due to its aggressive nature and limited treatment options. To address this, the study introduces the Tumor Mutational Burden-Derived Immune lncRNA Prognostic Index (TILPI) as a potential prognostic tool for SKCM. METHODS: TILPI was developed using a combination of gene set variation analysis, differential expression analysis,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39449143
DOI: 10.1186/s12967-024-05732-4
PMCID: PMC11515383

Genes

ADCY4
PRKACA
SOX10
STARD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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