Article

Prevalence of Pathogenic and Potentially Pathogenic Inborn Error of Immunity Associated Variants in Children with Severe Sepsis

2021-11-02

Abstract excerpt

<title>Abstract</title> <p>Purpose: Our understanding of inborn errors of immunity is increasing however, their contribution to pediatric sepsis is unknown. <h4>Methods:</h4> We used whole exome sequencing to characterize variants in genes related to monogenic immunologic disorders in 330 children admitted to intensive care for severe sepsis. We defined candidate variants as rare variants classified as pathogenic...

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Literature Corpus work: 60eb496e-ed37-5f3e-a08a-ed3ffa1c6ebd
DOI: 10.21203/rs.3.rs-366797/v2

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