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Article

Genome-wide association study of sepsis in extremely premature infants.

Archives of disease in childhood. Fetal and neonatal edition - 1 Sept 2017

Srinivasan Lakshmi, Page Grier, Kirpalani Haresh, Murray Jeffrey C, Das Abhik, Higgins Rosemary D, Carlo Waldemar A, Bell Edward F, Goldberg Ronald N, Schibler Kurt, Sood Beena G, Stevenson David K, Stoll Barbara J, Van Meurs Krisa P, Johnson Karen J, Levy Joshua, McDonald Scott A, Zaterka-Baxter Kristin M, Kennedy Kathleen A, Sánchez Pablo J, Duara Shahnaz, Walsh Michele C, Shankaran Seetha, Wynn James L, Cotten C Michael

Abstract excerpt

OBJECTIVE: To identify genetic variants associated with sepsis (early-onset and late-onset) using a genome-wide association (GWA) analysis in a cohort of extremely premature infants. STUDY DESIGN: Previously generated GWA data from the Neonatal Research Network's anonymised genomic database biorepository of extremely premature infants were used for this study. Sepsis was defined as culture-positive early-onset or...

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Identifiers

PMID: 28283553
DOI: 10.1136/archdischild-2016-311545
PMCID: PMC5563277

Genes

ELMO1
FOXC2
FOXL1
IRAK2
PIEZO2
RALA

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