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Article

Evaluation of epistasis detection methods for quantitative phenotypes.

Bioinformatics (Oxford, England) - 1 Jun 2026

Listopad Stanislav, Renjith Gauri, Peng Qian

Abstract excerpt

MOTIVATION: Epistasis, or genetic interaction, plays a crucial role in shaping complex traits and has been increasingly recognized for its widespread influence in genetic architectures. While epistasis detection has been extensively evaluated in case-control studies, its performance with quantitative phenotypes remains comparatively understudied. RESULTS: We identified and evaluated six epistasis detection...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 42241225
DOI: 10.1093/bioinformatics/btag344
PMCID: PMC13264488

Genes

DRD2
DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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