Article
The evolutionary landscape of host immunity genes involved in respiratory and other immune-related diseases, and the identification of TLR2 variation associated with severe COVID-19.
BMC biology - 29 May 2026
Cross Christopher N, Lisi Alessandro, Simmonds Faith C, Flores Marisol Fermin, Washington Kareem, Heinbockel Thomas, Campbell Michael C
Abstract excerpt
BACKGROUND: Given its high mortality and broad societal impact, the COVID-19 pandemic is arguably one of the most consequential public health crises of the twenty-first century. Although previous studies have identified several genes associated with COVID-19 susceptibility, relatively little is known about the genes contributing to severe COVID-19, including their evolutionary histories. In the current study, we...
Read the complete abstract on PubMedTopics
- Humans
- COVID-19
- Evolution, Molecular
- Genetic Predisposition to Disease
- Genetic Variation