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Article

The STK11 gene F354L mutation is associated with male spermatogenic dysfunction.

Scientific reports - 25 May 2026

Wan Neng, Huang Xiang, Jing Gang, Ren Laifeng

Abstract excerpt

To investigate the probability of the STK11 gene F354L mutation in normal individuals and infertile males with spermatogenic dysfunction, and to predict its impact on male spermatogenic function. We analyzed the F354L coding sequence in 192 azoospermia and severe oligozoospermia patients (patient group) and 199 normal fertile males (control group) using PCR and DNA sequencing. We detected 16 cases of the mutation...

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Share to AMP-Activated Protein Kinase Kinases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42185450
DOI: 10.1038/s41598-026-53888-4
PMCID: PMC13434688

Genes

STK11

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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