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Article

Some single-nucleotide polymorphisms of the TSSK2 gene may be associated with human spermatogenesis impairment.

Journal of andrology - 1 Jan 2000

Zhang Hao, Su Dan, Yang Yuan, Zhang Wei, Liu Yunqiang, Bai Gang, Ma Mingyi, Ma Yongxin, Zhang Sizhong

Abstract excerpt

Tssk2, a member of the testis-specific serine/threonine kinase (TSSK) family, is expressed predominantly in the testis and is crucial for the formation and function of sperm cells in the mouse. Targeted deletion of Tssk1 and Tssk2 in male chimeric mice caused infertility because of haploinsufficiency of the genes. Therefore, it is reasonable to postulate that mutations in the human homolog TSSK2 gene may also...

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Source

Identifiers

PMID: 19926886
DOI: 10.2164/jandrol.109.008466

Genes

TSSK2

Variants

rs1052763
rs3747052
rs1052756

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Some single-nucleotide polymorphisms of the TSSK2 gene may be associated with human spermatogenesis impairment.PMID 19926886Read ↗

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