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Article

Deep genotype imputation captures virtually all heritability of autoimmune vitiligo.

Human molecular genetics - 27 Mar 2020

Roberts Genevieve H L, Santorico Stephanie A, Spritz Richard A

Abstract excerpt

Autoimmune vitiligo is a complex disease involving polygenic risk from at least 50 loci previously identified by genome-wide association studies. The objectives of this study were to estimate and compare vitiligo heritability in European-derived patients using both family-based and 'deep imputation' genotype-based approaches. We estimated family-based heritability (h2FAM) by vitiligo recurrence among a total 8034...

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Identifiers

PMID: 31943001
DOI: 10.1093/hmg/ddaa005
PMCID: PMC7104671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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