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Article

Six decades of vitiligo genetics: genome-wide studies provide insights into autoimmune pathogenesis.

The Journal of investigative dermatology - 1 Feb 2012

Spritz Richard A

Abstract excerpt

Generalized vitiligo (GV) is a complex disease in which patchy depigmentation results from autoimmune loss of melanocytes from affected regions. Genetic analyses of GV span six decades, with the goal of understanding biological mechanisms and elucidating pathways that underlie the disease. The earliest studies attempted to describe the mode of inheritance and genetic epidemiology. Early genetic association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21993561
DOI: 10.1038/jid.2011.321
PMCID: PMC3258303

Genes

NLRP1
PTPN22
XBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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