Genome-wide analysis identifies a quantitative trait locus in the MHC class II region associated with generalized vitiligo age of onset.

doi:10.1038/jid.2011.12

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Article

Genome-wide analysis identifies a quantitative trait locus in the MHC class II region associated with generalized vitiligo age of onset.

The Journal of investigative dermatology - 1 Jun 2011

Jin Ying, Birlea Stanca A, Fain Pamela R, Gowan Katherine, Riccardi Sheri L, Holland Paulene J, Bennett Dorothy C, Herbstman Deborah M, Wallace Margaret R, McCormack Wayne T, Kemp E Helen, Gawkrodger David J, Weetman Anthony P, Picardo Mauro, Leone Giovanni, Taïeb Alain, Jouary Thomas, Ezzedine Khaled, van Geel Nanny, Lambert Jo, Overbeck Andreas, Spritz Richard A

Abstract excerpt

Generalized vitiligo is a common autoimmune disease in which acquired patchy depigmentation of skin, hair, and mucous membranes results from loss of melanocytes from involved areas. Previous genetic analyses have focused on vitiligo susceptibility, and have identified a number of genes involved in disease risk. Age of onset of generalized vitiligo also involves a substantial genetic component, but has not...

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PMID: 21326295
DOI: 10.1038/jid.2011.12
PMCID: PMC3172680

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BTNL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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