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Article

Functional analysis of a splicing variant of the DOCK8 gene in a patient with breast cancer (Buryat ethnicity).

Asian Pacific journal of cancer prevention : APJCP - 1 May 2026

Gervas Polina, Salakhov Ramil, Molokov Aleksey, Karpova Yuliya, Babyshkina Natalya, Buldakov Michail, Tsyganov Matvei, Molonova Lilya, Zarubin Alexey, Wang Lianhui, Choynzonov Eugene, Cherdyntseva Nadezda

Abstract excerpt

BRCA1/2 founder mutation have been detected in various populations and ethnicities. Molecular diagnosis of HBOC remains challenging for populations where founder mutations have not yet been identified. There are limited data on hereditary BC mutations in ethnic groups of Siberia. The purpose of this study was to find new hereditary breast cancer (BC) variants in the understudied Buryat ethnic group by using WES...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42169560
DOI: 10.31557/APJCP.2026.27.5.1559

Genes

DOCK8
FANCI
BRCA1
MLH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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