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Article

Whole Exome Sequencing Revealed Rare Variants in BRCA2, RAD51D, FANGC, CYP24A1 Genes in Breast/Ovarian Cancer Patients from a Small Buryat Ethnic Group.

Asian Pacific journal of cancer prevention : APJCP - 1 Feb 2026

Gervas Polina, Molokov Alexey, Babyshkina Nataliya, Ivanova Anna, Kollantay Olesya, Buldakov Mikhail, Molonova Liliya, Zarubin Alexey, Choynzonov Evgeny, Cherdyntseva Nadezda

Abstract excerpt

OBJECTIVE: Breast cancer is a public health problem with increasing incidence, prevalence, and mortality worldwide. Germline variants in the DNA repair genes BRCA1/2 are involved in the pathogenesis of hereditary breast/ovarian cancer. However, for many ethnic groups that are isolated geographically worldwide, founder variants of breast cancer still have not been found. In this study, we provide whole exome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41660923
DOI: 10.31557/APJCP.2026.27.2.651
PMCID: PMC13492716

Genes

RAD51D
BRCA2
CYP24A1
BRCA1
FANCG
FOXL2
GDF9
POLR2C

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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