Article

Unexpected High Frequency of Novel and Known Pathogenic Germline Variant of the Lgr4 Gene in the Ethnic Group of West Siberia

2024-09-02

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Hereditary breast cancer (BC) is an autosomal dominant disease caused by mutations in genes such as <italic>BRCA1/2, BRAD1, RAD54L, RAD51, ATM, BRIP1</italic>, and others. The prevalence and range of mutations can differ among various regions and ethnic groups. In a previous study using whole exome sequencing, we identified a germline pathogenic variant of the <...

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Literature Corpus work: 232b0755-e2d3-58de-9cda-1b1eeee33ab1
DOI: 10.21203/rs.3.rs-4761647/v1

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Unexpected High Frequency of Novel and Known Pathogenic Germline Variant of the Lgr4 Gene in the Ethnic Group of West SiberiaDOI 10.21203/rs.3.rs-4761647/v1Read

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