Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Geographic and genetic diversity in gallbladder cancer mutation profiles: insights from a worldwide exome analysis.

EBioMedicine - 1 Jun 2026

Gárate-Calderón Valentina, Kumar Rajiv, Marcelain Katherine, Zollner Linda, Boekstegers Felix, Barajas Olga, Loader Denisse, Rivera María Teresa, Morales Erik, de Toro Gonzalo, Caglevic Christian, Shibata Tatsuhiro, Lorenzo Bermejo Justo

Abstract excerpt

BACKGROUND: Gallbladder cancer (GBC), an aggressive disease with limited treatment options, occurs mainly in low-income and middle-income regions of Asia and Latin America. We analysed whole-exome sequencing data from 262 GBC tumour-normal sample pairs from Chilean, Chinese, Indian, Japanese and South Korean patients to investigate differences in GBC mutation profiles according to geographic location and genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exome
Share to Exome Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gallbladder Neoplasms

Share to TP53 gene

Share to Genetic Variation

Share to Geography

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 42167123
DOI: 10.1016/j.ebiom.2026.106305
PMCID: PMC13199658

Genes

MUC16
ARID2
ELF3
MACF1
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Geographic and genetic diversity in gallbladder cancer mutation profiles: insights from a worldwide exome analysis.PMID 42167123Read ↗

Genomic landscape of gallbladder cancer: insights from whole exome sequencing.Semantic proximity Read ↗

Clinical and Genomic Characterization of ERBB2-Altered Gallbladder Cancer: Exploring Differences Between an American and a Chilean Cohort.Semantic proximity Read ↗

Whole-exome and targeted gene sequencing of gallbladder carcinoma identifies recurrent mutations in the ErbB pathway.Semantic proximity Read ↗

Whole-exome mutational landscape of neuroendocrine carcinomas of the gallbladder.Semantic proximity Read ↗

Establishment and characterization of 38 novel patient-derived primary cancer cell lines using multi-region sampling revealing intra-tumor heterogeneity of gallbladder carcinoma.Semantic proximity Read ↗

Global patterns of mutational profiles in biliary tract cancer.Semantic proximity Read ↗

Integrative molecular characterisation of gallbladder cancer reveals micro-environment-associated subtypes.Semantic proximity Read ↗

Somatic genetic aberrations in gallbladder cancer: comparison between Chinese and US patientsSemantic proximity Read ↗

Gallbladder cancer in Chile: what have we learned?Semantic proximity Read ↗

Gallbladder adenocarcinomas undergo subclonal diversification and selection from precancerous lesions to metastatic tumorsSemantic proximity Read ↗

Gallbladder adenocarcinomas undergo subclonal diversification and selection from precancerous lesions to metastatic tumors.Semantic proximity Read ↗

Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.