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Ecotype-specific sensitivity to DNA methylation inhibitors in Arabidopsis cmt3 mutants.

Molecular genetics and genomics : MGG - 20 May 2026

Sun Xin, Du Guo, Kato Atsushi, Ito Hidetaka

Abstract excerpt

DNA methylation inhibitors such as 5-aza-2'-deoxycytidine (5-Aza-2dC) are widely used to probe epigenetic regulation, yet genetic factors underlying natural variation in inhibitor sensitivity remain poorly understood. Here, we investigated ecotype-specific responses to 5-Aza-2dC in Arabidopsis thaliana, focusing on cmt3 mutants in the Columbia (Col-0) and Landsberg erecta (Ler) backgrounds. We found...

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PMID: 42159606
DOI: 10.1007/s00438-026-02449-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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