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Article

Changes in global gene expression in response to chemical and genetic perturbation of chromatin structure.

PloS one - 1 Jan 2011

Hudson Karen, Luo Song, Hagemann Nicole, Preuss Daphne

Abstract excerpt

DNA methylation is important for controlling gene expression in all eukaryotes. Microarray analysis of mutant and chemically-treated Arabidopsis thaliana seedlings with reduced DNA methylation revealed an altered gene expression profile after treatment with the DNA methylation inhibitor 5-aza-2' deoxycytidine (5-AC), which included the upregulation of expression of many transposable elements. DNA damage-response...

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Identifiers

PMID: 21673996
DOI: 10.1371/journal.pone.0020587
PMCID: PMC3108824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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