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Article

Requirement of CHROMOMETHYLASE3 for maintenance of CpXpG methylation.

Science (New York, N.Y.) - 15 Jun 2001

Lindroth A M, Cao X, Jackson J P, Zilberman D, McCallum C M, Henikoff S, Jacobsen S E

Abstract excerpt

Epigenetic silenced alleles of the Arabidopsis SUPERMAN locus (the clark kent alleles) are associated with dense hypermethylation at noncanonical cytosines (CpXpG and asymmetric sites, where X = A, T, C, or G). A genetic screen for suppressors of a hypermethylated clark kent mutant identified nine loss-of-function alleles of CHROMOMETHYLASE3 (CMT3), a novel cytosine methyltransferase homolog. These cmt3 mutants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11349138
DOI: 10.1126/science.1059745

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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