Article
Reduced DNA methylation in Arabidopsis thaliana results in abnormal plant development.
Proceedings of the National Academy of Sciences of the United States of America - 6 Aug 1996
Finnegan E J, Peacock W J, Dennis E S
Abstract excerpt
Arabidopsis plants transformed with an antisense construct of an Arabidopsis methyltransferase cDNA (METI) have reduced cytosine methylation in CG dinucleotides. Methylation levels in progeny of five independent transformants ranged from 10% to 100% of the wild type. Removal of the antisense construct by segregation in sexual crosses did not fully restore methylation patterns in the progeny, indicating that...
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