Article
MTHFD1 controls DNA methylation in Arabidopsis.
Nature communications - 13 Jun 2016
Groth Martin, Moissiard Guillaume, Wirtz Markus, Wang Haifeng, Garcia-Salinas Carolina, Ramos-Parra Perla A, Bischof Sylvain, Feng Suhua, Cokus Shawn J, John Amala, Smith Danielle C, Zhai Jixian, Hale Christopher J, Long Jeff A, Hell Ruediger, Díaz de la Garza Rocío I, Jacobsen Steven E
Abstract excerpt
DNA methylation is an epigenetic mechanism that has important functions in transcriptional silencing and is associated with repressive histone methylation (H3K9me). To further investigate silencing mechanisms, we screened a mutagenized Arabidopsis thaliana population for expression of SDCpro-GFP, redundantly controlled by DNA methyltransferases DRM2 and CMT3. Here, we identify the hypomorphic mutant mthfd1-1,...
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