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Article

Genetically predicted stigmasterol and brain tumor risk: A Mendelian randomization study.

Medicine - 15 May 2026

Zhang Binbin, Gao Bolin, Yun Peng, Guo Shiwen, Liang Chen

Abstract excerpt

Stigmasterol, a plant-derived sterol involved in lipid metabolism, has been implicated in cancer-related biological processes. However, its causal relevance to brain tumor risk remains unclear. This study aimed to assess the causal relationships among genetically predicted stigmasterol levels, lipid metabolic traits, and brain tumor risk using Mendelian randomization (MR). Two-sample MR analysis was conducted...

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Identifiers

PMID: 42152379
DOI: 10.1097/MD.0000000000048870
PMCID: PMC13183147

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