Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypothyroidism and glioblastoma risk: a two-sample Mendelian randomization study.

Neuro endocrinology letters - 24 Mar 2026

Zhou Liying, Yin Changyou, Zhao Wei, Kong Wei, Wang Xuexin, Cui Guangqiang, Wang Yanbin

Abstract excerpt

BACKGROUND: Prior observational evidence suggests a potential link between hypothyroidism and glioblastoma (GBM) risk. To investigate causality, we conducted a two-sample Mendelian randomization (MR) study. METHODS: Between April 2025 and July 2025, we leveraged summary - level data from European - ancestry genome-wide association studies (GWAS). The inverse - variance weighted (IVW) approach served as the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Glioblastoma

Share to Hypothyroidism

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Identifiers

PMID: 41915925

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypothyroidism and glioblastoma risk: a two-sample Mendelian randomization study.PMID 41915925Read ↗

Testing for causality between systematically identified risk factors and glioma: a Mendelian randomization study.Semantic proximity Read ↗

Causal relationships of mental diseases and thyroid diseases based on a Mendelian randomization study.Semantic proximity Read ↗

Bidirectional 2-sample Mendelian randomization study of the causal relationship between hypothyroidism and cardiovascular diseases.Semantic proximity Read ↗

Hypothyroidism has a protective causal association with hepatocellular carcinoma: A two-sample Mendelian randomization studySemantic proximity Read ↗

The relationship between Alzheimer disease and thyroiditis: A two-sample Mendelian randomization study.Semantic proximity Read ↗

The causal relationship between multiple cardiovascular diseases and glioblastoma: A Mendelian randomization study.Semantic proximity Read ↗

Exploring the genetic link between hypothyroidism and osteoporosis in patients without cancer: a two-sample Mendelian randomization analysisSemantic proximity Read ↗

Subtype-specific causal effects of hypothyroidism on obstructive sleep apnea: A bidirectional Mendelian randomization studySemantic proximity Read ↗

Exploring the Causal Links Between Toxoplasma gondii Infection and Risk of Brain Tumors: A Bidirectional Mendelian Randomization Analysis.Semantic proximity Read ↗

Bioavailable testosterone and thyroid cancer: A 2-sample Mendelian randomization study.Semantic proximity Read ↗

Hypothyroidism and rheumatoid arthritis: a two-sample Mendelian randomization study.Semantic proximity Read ↗

Causal associations of hypothyroidism with frozen shoulder: a two-sample bidirectional Mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.